MedRelief is performing extensive basic science research primarily using in vitro studies with cell types such as osteoblasts and chondrocytes. Data from our cartilage cell studies shows early release of chemicals known to have a pain relieving effect on biological systems. Data from bone cell studies point to two findings; (1) a large increase in critical growth factors in the formation of bone; and (2) the production and organization, of mineralized bone tissue.

In order to gain the most comprehensive clinical data, our testing includes a range of studies from case studies; to uncontrolled pilot studies; to randomized, controlled, blinded trials.

• Case studies – individual and small groups used of MedRelief pain device showing reduction of pain for most patients

• Uncontrolled pilot studies – larger groups of 10 to 20 subjects showing successful pain reduction and patient compliance

• Randomized controlled clinical trials – large scale studies (around 100 subjects in multi-centered trials) designed to acquire definitive data to support additional claims

In pain relief applications, we want to establish clear effectiveness in specific painful conditions and potentially obtain additional labeling claims. For other healing applications, we will conduct basic, applied and clinical research as necessary to gain further FDA clearance.